- Make water-soluble nanoemulsions of lipophilic (oil-soluble) bio-active ingredients.
- Enhance the bioavailability and shorten the onset of action.
- Avoid having to develop formulations and processing procedures.
- Easily convert the nanoemulsions into water-soluble powders.
Overview
Companies that would like to produce their own water-soluble nanoemulsions of lipophilic (oil-soluble) bio-active compounds, such as cannabis extracts (a.k.a. water-soluble CBD, Delta 9, Delta 8 and Delta 10 THC, etc.), vitamins, essential oils, terpenes, nutraceuticals and pharmaceuticals, but do not have the capability or desire to develop formulations and processing procedures can take advantage of ISM’s All-In-One NanoStabilizer®-LSO. This proprietary blend of natural, organic, food-grade carrier oils, emulsifiers, and humectants is designed to work with our laboratory, bench and industrial ultrasonic processors and comes with step-by-step processing instructions. NanoStabilizer®-LSO is tasteless, provides bitter taste masking and makes it possible to easily and quickly produce permanently stable and fully water-compatible liquid and powdered nanoemulsions with median droplet sizes in the range of 150 – 200 nanometers. Water-soluble powders prepared with this product reconstitute back into liquid nanoemulsions upon contact with water.
What is needed to produce water-soluble bio-active powders?
Much like our NanoStabilizer®-LT formulation, NanoStabilizer®-LSO makes it possible for both the novice and professional to easily produce water-soluble bio-active powders to add to beverages and edibles or to be consumed directly as fast-dissolving tablets, utilizing the following components:
- ISM high-intensity ultrasonic processor, high-pressure homogenizer, or similar
- NanoStabilizer®-LSO
- Oil-soluble bio-active ingredient
- Distilled water
- Drying method/equipment
Science in a Jar
NanoStabilizer®-LSO is much more than just an enabling product. It is an essential element of an elegant, cost-effective and complete solution designed to help you make water-soluble CBD/THC and other bio-active liquids and powders without having to develop formulations, as we have already done it for you. NanoStabilizer®-LSO is an all-natural and organic product with the following distinct advantages:
- Flavor Masker. ISM has built an integrated flavor masker into the NanoStabilizer®-LSO formula, which enables customers to make liquid or powdered nanoemulsions that can be added to multiple types of finished products without altering their original taste.
- Bioavailability Enhancer. NanoStabilizer®-LSO provides the foundation for our customers to create water-soluble nanoemulsions, thereby making the incorporated bio-active ingredients highly bioavailable. Additionally, this formulation significantly shortens the onset times and ensures reproducible product performance.
- Direct Drying. Nanoemulsions based on NanoStabilizer®-LSO can be dried directly (with nothing added) via multiple drying methods.
- Reconstitution Intelligence. Once added to water, bio-active powders created with NanoStabilizer®-LSO reconstitute into the original nanoemulsions, enabling the producer to remain true to their intended bioavailability profiles and other pharmacokinetic requirements.
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Frequently Asked Questions
What is NanoStabilizer®-LSO?
NanoStabilizer®-LSO is ISM’s all-natural, organic nano emulsifier — a proprietary, ready-to-use blend of food-grade carrier oils, emulsifiers, and humectants. It is designed to work with ISM ultrasonic processors to enable companies to produce permanently stable, water-soluble nanoemulsions and powders of lipophilic (oil-soluble) bioactive ingredients, including CBD, THC, vitamins, essential oils, terpenes, and nutraceuticals — without requiring in-house formulation expertise.
What is NanoStabilizer®-LSO used for?
NanoStabilizer®-LSO is used to produce water-soluble nanoemulsions with droplet sizes of 150–200 nanometers, and to convert those nanoemulsions into water-soluble powders. It is most commonly used for cannabis extracts (water-soluble CBD, Delta 8, Delta 9, Delta 10 THC), vitamins, terpenes, essential oils, and other lipophilic nutraceutical and pharmaceutical compounds. The resulting products can be added to beverages, edibles, or consumed as fast-dissolving tablets.
Is NanoStabilizer®-LSO all-natural and organic?
Yes. NanoStabilizer®-LSO is an all-natural and organic formulation made from food-grade carrier oils, emulsifiers, and humectants. It is tasteless and includes an integrated bitter taste masker, making it suitable for beverages and edibles without altering the original product flavor.
What equipment is needed to use NanoStabilizer®-LSO?
You need an ISM high-intensity ultrasonic processor (LSP-600, BSP-1200, or ISP-3600), or a comparable high-pressure homogenizer. Additional requirements include NanoStabilizer®-LSO, your oil-soluble bioactive ingredient, distilled water, and drying equipment if producing powders. Step-by-step processing instructions are included with each purchase.
What is the difference between NanoStabilizer®-LSO and NanoStabilizer®-LT?
Both are all-in-one nano emulsifier formulations, but they are designed for different end products. NanoStabilizer®-LSO is optimized for producing water-soluble powders — nanoemulsions made with LSO can be dried directly without additives and reconstitute into the original nanoemulsion on contact with water. NanoStabilizer®-LT is formulated for stable liquid nanoemulsions. Consult ISM’s application specialists to determine which formulation best fits your production goals.
