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    Nanoemulsions & Liposomes

    Manufacture pharmaceutical, food and cosmetic nanoemulsions, nanocrystals and liposomes.

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    Medical Cannabis Formulations

    Produce water‑soluble CBD and THC nanoemulsions with enhanced bioavailability and rapid action.

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    Degassing of liquids

    Remove dissolved gases and micro‑bubbles from oils, waxes, detergents and adhesives.

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    Cell Distruption & Extraction

    Extract oils and recover bioactive compounds
    by lysing plant and microbial cells.

  • Nanoemulsions & Liposomes

    Nanoemulsions & Liposomes

    Manufacture pharmaceutical, food and cosmetic nanoemulsions, nanocrystals and liposomes.

  • Medical Cannabis Formulations

    Medical Cannabis Formulations

    Produce water‑soluble CBD and THC nanoemulsions with enhanced bioavailability and rapid action.

  • Degassing of liquids

    Degassing of liquids

    Remove dissolved gases and micro‑bubbles from oils, waxes, detergents and adhesives.

  • Cell Disruption and Extraction

    Cell Distruption & Extraction

    Extract oils and recover bioactive compounds
    by lysing plant and microbial cells.

Ultrasonic Processors

LSP-600
Laboratory-Scale Processor
BSP-1200
Bench-Scale Processor
ISP-3000
Industrial-Scale Processor

make your own nanoformulations

on any scale

ISM is a research & development, equipment design and process consulting firm, specializing in scalable high-intensity ultrasonic technology. We focus on providing the tools to make nanoemulsions, nanocrystals, and liposomes to the pharmaceutical, cosmetic, medical cannabis, and food & beverage industries. Other target applications include cell disruption, aqueous and solvent-based oil extraction, liquid degassing, nanoparticle deagglomeration, and sonochemistry. Our mission is to enable our clients to optimize these ultrasonic processes and implement them in commercial production.

Have Questions?

Consult with an application specialist
or request a quotation.

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  • What is BHUT?

AP presentation
12/03/19

Presentation Recording, 2019 Cannabis Drinks Expo, San Francisco, CA

We are happy to announce that the recording of Dr. Alexey Peshkov... Read more...
Main nanoemulsion destabilization pathways. 
10/08/19

How to Formulate Cannabis Extract Nanoemulsions with a Long Shelf Life

One of the primary concerns when formulating oil-in-water (O/W) n... Read more...
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08/22/19

ISM will Present at the 2019 CannaCon Expo in Springfield, MA

Read more...

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All-Natural CBD Extract Nanoemulsion
CASE STUDY

Download PDF

Ultrasonic Nanocrystallization
CASE STUDY

Download PDF

Ultrasonic Disruption of Yeast Cells
CASE STUDY

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Scaling Up the Production of a Nanoemulsion
CASE STUDY

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Khara Cartagena, Cannabis and Hemp ProductionsMay 2016

"We recently purchased a BSP-1200 system from ISM and were very impressed with its performance. The word got out, and one of our customers came to our facility to perform CBD-oil emulsion tests with the system. Though he was initially skeptical, after running the machine for only 1 min he got far better results to what he was able to achieve in over an hour with his conventional ultrasonic processor. He absolutely loved the BSP-1200 and bought it off from us that same day to take to his facility in CA! We have now decided to go straight for ISM's production-scale ISP-3000 processor."

See all testimonials

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EFFICIENT COOLING OF PIEZOELECTRIC TRANSDUCERS

United States Patent # 9,142,751, September 22, 2015

Alexey S. Peshkovsky, Sergei L. Peshkovsky

Abstract: A sealed piezoelectric transducer having a single, uniform, electrically insulating, heat-conducting layer of a soft, rubbery material filled with a fine, homogeneously-dispersed powder having high thermal conductivity. The material is placed in contact with the surfaces of the transducer and conducts the heat from the surfaces to an external heat sink. Since the thermally conductive powder is fully encapsulated in the rubbery material, its abrasive properties are neutralized.

See all intellectual property

Download PDF

See all patents

High ultrasonic amplitudes able to generate intense acoustic cavitation are required for most processes.

Unlike conventional ultrasonic devices, our patented Barbell Horn Ultrasonic Technology (BHUT)-based processors make it possible to produce extremely high ultrasonic amplitudes at any scale, from laboratory to industrial, guaranteeing reproducible results after scale-up.

Learn More

Introduction to Industrial Sonomechanics’ Proprietary Barbell Horn Ultrasonic Technology (BHUT)
Water-Soluble Cannabis Extract Nanoemulsions, by Dr. Alexey Peshkovsky, Industrial Sonomechanics
Why and How to Make Cannabis Extracts “Water-Soluble” – a Presentation by Dr. Alexey Peshkovsky
Can CBD or THC be Made Water-Soluble? Manufacturing and Dosing Translucent Cannabis Extract Nanoemulsions
Ultrasonics 2016 Conference Presentation by Dr. Alexey Peshkovsky, President & Chief Scientific Officer of ISM
Translucent Nanoemulsion Produced with ISM Industrial-Scale Ultrasonic Liquid Processor, ISP-3000
BSP-1200 Bench-Scale Ultrasonic Processor: Barbell Horn Replacement Procedure
Webcast Recording: Ultrasonic Liquid Processing for Cannabis Oil Nano-Emulsification and Extraction
Watch All videos

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Phone: +1-646-580-HORN (4676)
Address:
7440 SW 50th Terrace #110
Miami, FL 33155
Address: 7440 SW 50th Terrace #110 Miami, FL 33155
Email: contact@sonomechanics.com
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