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Home > Medical Cannabis

Medical Cannabis

medical cannabis_1
  • Make water-soluble CBD and THC nanoemulsions with enhanced bioavailability and rapid onset of action.
  • Ensure precise and reproducible therapeutic dosing.
  • Infuse water with a strong dose of cannabinoids while retaining optical clarity.
  • Extract cannabis oil using water as a solvent.

Overview

Medicinal uses of cannabis have now been legalized in a number of countries and most of the United States. Unfortunately, none of the existing routes of administering this medicine, including pulmonary, sublingual, transbuccal, transdermal and oral, make it possible to deliver predictable doses of cannabinoids to their target sites. Cannabis extracts are hydrophobic (incompatible with water) and, as such, difficult to deliver to the water-based bloodstream. When consumed orally, for example, they undergo a slow process of gastrointestinal absorption, leading to a delayed onset of action as well as a low (6 – 10%) and unpredictable bioavailability. 

Our patented Barbell Horn® Ultrasonic Technology (BHUT) and over a decade of experience in the pharmaceutical industry enables us to offer a very effective solution: cannabis extract nanoemulsions. These formulations are fully water-compatible, kinetically stable, provide exceptional therapeutic effects, and are absorbed by the body very rapidly and completely, exhibiting higher potency and faster onset of action for lower doses. Since nanoemulsions can be made translucent, they are easily mixed into water (or any other beverage) without compromising its optical clarity. In addition, since our technology makes oils water-compatible (aka. water-soluble), it can be used to extract cannabis oil from plants directly into water, avoiding dangerous organic solvents. With Industrial Sonomechanics® laboratory, bench, and industrial ultrasonic systems, these processes can be implemented at any scale of operation, guaranteeing reproducible and predictable results.
cannabis-plant-ultrasonic processing

Case Studies & Application Reports

All-Natural CBD Extract Nanoemulsion
CASE STUDY
Download PDF Translucent Nanoemulsion of CBD Concentrate
Ultrasonic Nanocrystallization of Nifedipine
CASE STUDY
Download PDF nanocrystallization of nifedipine
Nanoemulsions Used for Parenteral Nutrition
APPLICATION REPORT
Download PDF Nanoemulsions Used for Parenteral Nutrition
Drug Carrier Liposomes and Nanoemulsions
APPLICATION REPORT
Download PDF drug carrier liposomes and nanoemulsions
View all case studies

Blog Posts

How Stable Are Nanoemulsions Made with NanoStabilizer®-LT and NanoStabilizer®-LSO? Here's the Data.
04/14/25

How Stable Are Nanoemulsions Made with NanoStabilizer®-LT and NanoStabilizer®-LSO? Here's the Data.

One of the most common questions we receive from customers is about the long-term stabil... Read more...
Using a High-Pressure Homogenizer? Produce Superior Nanoemulsions with All-In-One NanoStabilizers®
02/12/25

Using a High-Pressure Homogenizer? Produce Superior Nanoemulsions with All-In-One NanoStabilizers®

All-In-One NanoStabilizers® have transformed the cannabis and nutraceutical industries b... Read more...
Highly Concentrated Nanoemulsions With Sub-100 nm Droplets: Here’s How to Make Them
02/03/25

Highly Concentrated Nanoemulsions With Sub-100 nm Droplets: Here’s How to Make Them

Producing fast-acting, highly bioavailable, readily water-soluble nanoemulsions of bioac... Read more...
Read all Blog Posts

Customer Testimonials

Khara Cartagena, Cannabis and Hemp Productions

“We recently purchased a BSP-1200 system from ISM and were very impressed with its performance. The word got out, and one of our customers came to our facility to perform CBD-oil emulsion tests with the system. Though he was initially skeptical, after running the machine for only 1 min he got far better results to what he was able to achieve in over an hour with his conventional ultrasonic processor. He absolutely loved the BSP-1200 and bought it off from us that same day to take to his facility in CA! We have now decided to go straight for ISM’s production-scale ISP-3000 processor.”
See more Customer Testimonials

Videos

  • ISM’s Barbell Horn Ultrasonic Technology Introduction and How We Scale Up
  • Can CBD or THC be Made Water-Soluble with ISM’s Ultrasonic Technology?
  • Making a Translucent Nanoemulsion with ISP-3000 in the Flow-Through Mode
Watch All videos

Ebooks

  • MAKING STABLE EMULSIONS: A Guide to Formulation and Processing Conditions Optimization
    Download PDF

FAQs

  • CANNABIS PROCESSING: Frequently Asked Questions
    Read FAQs

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