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    WATER-SOLUBLE CANNABIS FORMULATIONS

    Produce your own water-soluble THC and CBD nanoemulsions. No technical background needed.

    • Create fast-acting & highly bioavailable liquids and powders.
    • Follow our detailed SOPs for optimal results.
    Schedule A Call
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    NANOEMULSIONS, LIPOSOMES & MORE

    Manufacture pharmaceutical, nutraceutical, food & beverage, and cosmetic nano-formulations.

    • Create fast-acting and highly bioavailable liquids and powders.
    • Use our custom formulation development services.
    Schedule A Call
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    IN-LINE DEGASSING & DEHYDRATION

    Remove dissolved/entrained gases and water from fuels, oils, waxes, detergents, and adhesives.

    • Improve performance by preventing oxidation or increased conductivity.
    • Improve visual appearance and filling operations.
    Schedule A Call
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    EXTRACTION BY CELL DISRUPTION

    Extract a wide range of active ingredients from mushrooms, plants and microorganisms.

    • Increase extraction rates and product yields, simplify post-processing procedures.
    • Replace harsh organic solvents with green alternatives.
    Schedule A Call
  • water soluble cannabis formulations by sonomechanics

    WATER-SOLUBLE CANNABIS EXTRACTS

    Produce your own water-soluble THC and CBD nanoemulsions. No technical background necessary.

    • Create fast-acting and highly bioavailable liquid and powdered cannabis nano-formulations.
    • Follow our detailed SOPs for optimal results.
    Schedule A Call
  • nanoemulsion and liposomes production equipment sonomechanics

    NANOEMULSIONS, LIPOSOMES & MORE

    Manufacture pharmaceutical, nutraceutical, food & beverage, and cosmetic nano-formulations.

    • Create fast-acting and highly bioavailable liquid and powdered nano-formulations.
    • Use our custom formulation development services.
    Schedule A Call
  • liquid degassing equipment by sonomechanics

    IN-LINE DEGASSING & DEHYDRATION

    Remove dissolved/entrained gases and water from fuels, oils, waxes, detergents, and adhesives.

    • Improve performance by preventing oxidation, increased conductivity, and other unwanted processes.
    • Improve visual appearance and filling operations.
    Schedule A Call
  • cell disruption extraction equipment by sonomechanics

    EXTRACTION BY CELL DISRUPTION

    Extract a wide range of active ingredients from mushrooms, plants and microorganisms.

    • Increase extraction rates and product yields, simplify post-processing procedures.
    • Replace harsh organic solvents with green alternatives.
    Schedule A Call
  • water soluble cannabis formulations by sonomechanics

    WATER-SOLUBLE CANNABIS FORMULATIONS

    Produce your own water-soluble THC and CBD nanoemulsions. No technical background needed.

    • Create fast-acting and highly bioavailable liquid and powdered cannabis nano-formulations.
    • Follow our detailed SOPs for optimal results.
    Schedule A Call
  • nanoemulsion and liposomes production equipment sonomechanics

    Nanoemulsions, Liposomes & more

    Manufacture pharmaceutical, nutraceutical, food & beverage, and cosmetic nano-formulations.

    • Create fast-acting and highly bioavailable liquid and powdered nano-formulations.
    • Use our custom formulation development services.
    Schedule A Call
  • liquid degassing equipment by sonomechanics

    In-Line Degassing & Dehydration

    Remove dissolved/entrained gases and water from fuels, oils, waxes, detergents, and adhesives.

    • Improve performance by preventing oxidation, increased conductivity, and other unwanted processes.
    • Improve visual appearance and filling operations.
    Schedule A Call
  • extraction by cell disruption equipment by sonomechanics

    Extraction by Cell Disruption

    Extract a wide range of active ingredients from mushrooms, plants and microorganisms.

    • Increase extraction rates and product yields, simplify post-processing procedures.
    • Replace harsh organic solvents with green alternatives.
    Schedule A Call

Ultrasonic Processors

ISM is a research & development, equipment design and process consulting firm, specializing in
scalable high-intensity ultrasonic technology.

High Ultrasonic Amplitudes

High Ultrasonic Amplitudes

Generate unprecedented cavitation & shear force intensities at any scale, from lab to industrial.

Seamless Scale-Up

Seamless Scale-Up to Production

Transfer from the lab to production while maintaining the highest finished product quality.

24/7 Production-Scale Processing

24/7 Production-Scale Processing

Continuously operate the equipment for as long as required, without interruptions.

Wide-Range Temperature Control

Precise Temperature Control

Maintain the temperature of your liquid material at any desired
level in a wide range.

LSP-600
Laboratory-Scale Processor
BSP-1200
Bench-Scale Processor
ISP-3600
Industrial-Scale Processor

Have Questions?

Consult with an application specialist
or request a quotation.

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  • Blog
  • Blog
  • Case Studies
  • Testimonials
  • Intellectual Property
  • What is BHUT?
How Stable Are Nanoemulsions Made with NanoStabilizer®-LT and NanoStabilizer®-LSO? Here's the Data.
04/14/25

How Stable Are Nanoemulsions Made with NanoStabilizer®-LT and NanoStabilizer®-LSO? Here's the Data.

One of the most common questions we receive from customers is about ... Read more...
Using a High-Pressure Homogenizer? Produce Superior Nanoemulsions with All-In-One NanoStabilizers®
02/12/25

Using a High-Pressure Homogenizer? Produce Superior Nanoemulsions with All-In-One NanoStabilizers®

All-In-One NanoStabilizers® have transformed the cannabis and nutrac... Read more...
Highly Concentrated Nanoemulsions With Sub-100 nm Droplets: Here’s How to Make Them
02/03/25

Highly Concentrated Nanoemulsions With Sub-100 nm Droplets: Here’s How to Make Them

Producing fast-acting, highly bioavailable, readily water-soluble na... Read more...
Read all blog posts
All-Natural CBD Extract Nanoemulsion
CASE STUDY

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Ultrasonic Nanocrystallization
CASE STUDY

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Ultrasonic Disruption of Yeast Cells
CASE STUDY

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Scaling Up the Production of a Nanoemulsion
CASE STUDY

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Khara Cartagena, Cannabis and Hemp Productions

“We recently purchased a BSP-1200 system from ISM and were very impressed with its performance. The word got out, and one of our customers came to our facility to perform CBD-oil emulsion tests with the system. Though he was initially skeptical, after running the machine for only 1 min he got far better results to what he was able to achieve in over an hour with his conventional ultrasonic processor. He absolutely loved the BSP-1200 and bought it off from us that same day to take to his facility in CA! We have now decided to go straight for ISM’s production-scale ISP-3000 processor.”

See all testimonials

See all testimonials

EFFICIENT COOLING OF PIEZOELECTRIC TRANSDUCERS

United States Patent # 9,142,751, September 22, 2015

Alexey S. Peshkovsky, Sergei L. Peshkovsky

Abstract: A sealed piezoelectric transducer having a single, uniform, electrically insulating, heat-conducting layer of a soft, rubbery material filled with a fine, homogeneously-dispersed powder having high thermal conductivity. The material is placed in contact with the surfaces of the transducer and conducts the heat from the surfaces to an external heat sink. Since the thermally conductive powder is fully encapsulated in the rubbery material, its abrasive properties are neutralized.

See all intellectual property

Download PDF

See all patents

High ultrasonic amplitudes able to generate intense acoustic cavitation are required for most processes.

Unlike conventional ultrasonic devices, our patented Barbell Horn Ultrasonic Technology (BHUT)-based processors make it possible to produce extremely high ultrasonic amplitudes at any scale, from laboratory to industrial, guaranteeing reproducible results after scale-up.

Learn More

 
Newest Advancements in ISM Ultrasonic Technology and Nano-Formulations
Water-Soluble Cannabinoids, Alkaloids & Other Bioactives: 2023 NECANN
Large-Capacity In-Line Filter: Assembly, Nanoemulsion Filtration, Cleaning, & Storage Procedures
Industrial Sonomechanics® at MJBizCon 2021 in Las Vegas, NV
“Water-Soluble” Cannabis: Ultrasonic Production of Liquid & Powdered Nanoemulsions
Barbell Horn Ultrasonic Technology (BHUT) Introduction and How We Scale Up
Interview with Dr. Alexey Peshkovsky at 2021 CBDExpo
Overview of Nano-Emulsification Process with BSP-1200 Ultrasonic Processor
Water-Soluble Cannabis Extract Nanoemulsions, by Dr. Alexey Peshkovsky, Industrial Sonomechanics
Dr. Alexey Peshkovsky speaking at the University of Cauca, Colombia
Podcast: Make & Measure the Potency of Cannabis Extract Nanoemulsions
Plant 2 Product: Production of Cannabis Beverages & Water-Soluble Powders
Barbell Horn Replacement Procedure for ISM Ultrasonic Processors
Do I Need Technical Background to Make Nanoemulsions with ISM Technology
 
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